先天性肾积水时肾盂输尿管连接处的组织学 findings（此处“findings”可结合上下文灵活准确翻译，比如“表现”等，因未明确完整语境，暂保留英文）（作者译）

[Histological findings of the ureteropelvic junction in congenital hydronephrosis (author's transl)].

作者信息

Fladerer H, Hubmer G

出版信息

Urol Int. 1975;30(5):350-6. doi: 10.1159/000279999.

Abstract

Histological investigation of ureteropelvic junction (UPJ) specimens of 21 patients with congenital hydronephrosis revealed in 7 instances pathological changes, which might be responsible for the obstruction. In 15 cases a significant increase of collagenous tissue within the UPJ, along with a relative deficiency of monocytes was noted. Each of the smooth muscle fibers was surrounded by fibrous tissue, which caused interruption of the "nexus" function and therefore loss of muscle contractions. The inability of normal muscle contractions within the UPJ might be a contributing factor to the pathogenesis of congenital hydronephrosis.

摘要

对21例先天性肾积水患者的肾盂输尿管连接部（UPJ）标本进行组织学研究发现，7例存在可能导致梗阻的病理变化。15例患者的UPJ内胶原组织显著增加，同时单核细胞相对缺乏。每条平滑肌纤维都被纤维组织包围，这导致“连接”功能中断，从而使肌肉收缩丧失。UPJ内正常肌肉收缩功能的丧失可能是先天性肾积水发病机制的一个促成因素。