Luukkainen R K, Wennerstrand P V, Kautiainen H H, Sanila M T, Asikainen E L
Satalinna Hospital, Harjavalta, Finland.
Clin Exp Rheumatol. 2002 Jan-Feb;20(1):52-4.
To investigate the efficacy of periarticular corticosteroid treatment of the sacroiliac joint (SIJ) in non-spondylarthropathic patients with chronic low back pain in the region of the SIJ in a double blind, controlled study.
Twenty-four consecutive non-spondylarthropathic patients with chronic pain in the region of the SIJ entered the study. Thirteen patients were treated with a periarticular injection of methylprednisoloneacetate and lidocaine (MP group) of the SIJ, whereas 11 patients received isotonic sodium chloride and lidocaine. Clinical assessment at the onset of the study and after one month included the patient's estimation of pain in the region of the SIJ by the visual analogue scale (VAS) and by a pain index, which was calculated from tenderness and stressing tests on the SIJ.
At the one month's follow-up examination both the VAS (p = 0.047) and the pain index (0.017) had improved significantly in the MP group compared with the non-MP group.
These results suggest that periarticular injection of methylprednisolone may be effective in the treatment of pain in the region of the SIJ in non-spondylarthropathic patients.
在一项双盲对照研究中，调查关节周围注射皮质类固醇治疗非脊柱关节病性慢性下腰痛患者骶髂关节（SIJ）区域疼痛的疗效。
24例连续的非脊柱关节病性骶髂关节区域慢性疼痛患者进入本研究。13例患者接受骶髂关节周围注射醋酸甲基泼尼松龙和利多卡因（MP组），而11例患者接受等渗氯化钠和利多卡因注射。研究开始时和1个月后进行临床评估，包括患者通过视觉模拟量表（VAS）和疼痛指数评估骶髂关节区域的疼痛，疼痛指数由骶髂关节压痛和应力试验计算得出。
在1个月的随访检查中，与非MP组相比，MP组的VAS（p = 0.047）和疼痛指数（0.017）均有显著改善。
这些结果表明，关节周围注射甲基泼尼松龙可能对治疗非脊柱关节病性患者骶髂关节区域的疼痛有效。
