Ma Z, Florjancic A S
Infectious Disease Research, Abbott Laboratories, Abbott Park, IL 60064-3537, USA.
Curr Opin Investig Drugs. 2001 Dec;2(12):1702-5.
Aventis Pharma (formerly Hoechst Marion Roussel) is investigating the ketolides HMR-3562 and HMR-3787 as potential antibacterial agents. The compounds belong to a series of 2-fluoroketolides. They have exhibited potency against a range of gram-positive bacteria and other respiratory tract pathogens including Haemophilus influenzae in vitro and in vivo.
安万特制药公司（原赫斯特·马里恩·罗氏公司）正在研究酮内酯类药物HMR - 3562和HMR - 3787作为潜在的抗菌剂。这些化合物属于一系列2 - 氟酮内酯类。它们在体外和体内对一系列革兰氏阳性菌以及包括流感嗜血杆菌在内的其他呼吸道病原体均显示出抗菌活性。
