MMWR Morb Mortal Wkly Rep. 2002 Feb 8;51(5):97-101.
Since 1983, when the first infant was conceived from in vitro fertilization (IVF) in the United States, the use of IVF and related procedures (assisted reproductive technology [ART]) has increased substantially. In 1998, an estimated 0.7% of the 3.9 million births were the result of ART. ART patients are more likely to deliver multiple infants than women who conceive without treatment, and these multiple-infant births are associated with increased risks for pregnancy complications, premature delivery, low birth-weight infants, and long-term disability among surviving infants. This report examines state-specific use of ART in 1996 and 1998 and provides data on ART live-born and multiple-infant birth rates in 1998. Findings indicate that the use of ART is increasing in most states and that more than half the infants born as a result of these procedures are multiple births. These high-risk births contribute disproportionately to health-care costs and might negatively affect maternal and child health outcomes, particularly in states where large numbers of ART procedures are performed.
自1983年美国首例通过体外受精（IVF）受孕的婴儿诞生以来，IVF及相关程序（辅助生殖技术[ART]）的使用大幅增加。1998年，在390万例出生中，估计有0.7%是ART的结果。与未经治疗而受孕的女性相比，ART患者更有可能产下多胞胎，而这些多胞胎分娩与妊娠并发症、早产、低体重儿以及存活婴儿的长期残疾风险增加有关。本报告考察了1996年和1998年各州ART的使用情况，并提供了1998年ART活产率和多胞胎出生率的数据。研究结果表明，大多数州ART的使用都在增加，并且通过这些程序出生的婴儿中，超过一半是多胞胎。这些高风险分娩对医疗保健成本的贡献不成比例，可能会对母婴健康结果产生负面影响，尤其是在进行大量ART程序的州。
