Chapin Robert E, Robbins Wendie A, Schieve Laura A, Sweeney Anne M, Tabacova Sonia A, Tomashek Kay M
Pfizer Global Research and Development, Safety Sciences, Eastern Point Road, MS 8274-1336, Groton, CT 06340, USA.
Environ Health Perspect. 2004 Jan;112(1):69-78. doi: 10.1289/ehp.6261.
The scientific community is developing a compelling body of evidence that shows the importance of the in utero environment (including chemical and hormonal levels) to the ultimate health of the child and even of the aging adult. This article summarizes the evidence that shows this impact begins with conception. Only a full life-cycle evaluation will help us understand these impacts, and only such an understanding will produce logically prioritized mitigation strategies to address the greatest threats first. Clearly, the time for analysis begins when the next generation is but a twinkle in the eye.
科学界正在积累越来越多有说服力的证据，表明子宫内环境（包括化学物质和激素水平）对儿童乃至成年后的健康至关重要。本文总结了表明这种影响始于受孕的证据。只有进行完整的生命周期评估，才能帮助我们理解这些影响，而只有这样的理解才能产生逻辑上优先排序的缓解策略，以便首先应对最大的威胁。显然，分析工作应从下一代还只是一个设想时就开始。
