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[腹腔间隔室综合征]

[Abdominal compartment syndrome].

作者信息

Decker G

机构信息

Service de Chirurgie Viscérale, Centre Hospitalier de Luxembourg, 4, rue E. Barblé, L-1210 Luxembourg.

出版信息

J Chir (Paris). 2001 Oct;138(5):270-6.

Abstract

Abdominal compartment syndrome (ACS) is defined by the deleterious effects of intraabdominal hypertension (IAH) on the pulmonary, cardiovascular, splanchnic, urinary and central nervous system. Abnormal and sudden increase in the volume of any component of the intraperitoneal or retroperitoneal space (occurRing postoperatively or subsequent to hemorrhagic trauma, referfusion edema, penumoperitoneum, intestinal distention, acute pancreatitis...) causes IAH. Sustained IAH leads to ACS which if left unrecognized or untreated is always fatal. Measurement of urinary bladder pressure is the best validated technique for diagnosis of IAH. It should be used routinely for minimally invasive surveillance of intra-abdominal pressure (IAP) in patients with severe thoraco-abdominal trauma or after major abdominal operations. Medical management of IAH is of limited efficacy making expedient surgical decompression the treatment of choice for ACS. Surgical decompression of the abdomen and temporary closure is generally recognized as effective in clinically patent ACS but the pressure threshold indicating the need for decompression remains controversial. No data are available from controlled randomized trials and current guidelines are based on the experience of large trauma centers. The few available prospective clinical series report survival rates in the 38 to 71% range after surgical decompression for ACS. These studies are difficult to compare due to methodological features but it would appear that centers using the lowest pressure threshold for decompensation (< 20 mmHg) have the highest survival rates. Despite the available physiological arguments, indications for prophylactic temporary abdominal coverage (TAC), e.g. in trauma patients or for early decompression in IAH patients without clinical ACS, have not been validated in clinical practice. The potential morbidity of decompression procedures, TAC, and subsequent abdominal wall reconstructions require comparative studies of these treatment options with available pharmacological and non-surgical means to lower IAP.

摘要

腹腔间隔室综合征(ACS)是由腹腔内高压(IAH)对肺、心血管、内脏、泌尿和中枢神经系统产生的有害影响所定义的。腹腔或腹膜后间隙任何成分的异常和突然增加(发生在术后或出血性创伤、再灌注水肿、气腹、肠扩张、急性胰腺炎之后……)都会导致IAH。持续的IAH会导致ACS,如果未被识别或未得到治疗,往往是致命的。测量膀胱压力是诊断IAH最有效的技术。对于严重胸腹创伤患者或腹部大手术后的患者,应常规使用该技术进行腹腔内压力(IAP)的微创监测。IAH的药物治疗效果有限,因此紧急手术减压是ACS的首选治疗方法。腹部手术减压并临时关闭通常被认为对临床确诊的ACS有效,但表明需要减压的压力阈值仍存在争议。目前尚无来自对照随机试验的数据,当前指南基于大型创伤中心的经验。少数现有的前瞻性临床系列报道了ACS手术减压后的生存率在38%至71%之间。由于方法学特点,这些研究难以比较,但似乎使用最低减压压力阈值(<20 mmHg)的中心生存率最高。尽管有生理学依据,但预防性临时腹部覆盖(TAC)的适应症,例如在创伤患者中或在没有临床ACS的IAH患者中进行早期减压,在临床实践中尚未得到验证。减压手术、TAC以及随后的腹壁重建的潜在发病率需要对这些治疗选择与可用的药理学和非手术降低IAP方法进行比较研究。

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