Abonia J Pablo, Castells Mariana C
Harvard Medical School, the Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Allergy Asthma Proc. 2002 Jan-Feb;23(1):53-7.
We present a case report and review of the literature that illustrates many key features of patients with common variable immunodeficiency (CVID). These patients frequently present with repeated infections with a variety of different microorganisms. Recurrent sinopulmonary infections can lead to serious chronic complications such as bronchiectasis, and gastrointestinal infections can result in malabsorption. In addition to serious infection, CVID is associated with a number of comorbid disorders including a variety of autoimmune diseases and neoplasms. Here, we provide an illustrative case report and discuss the primary features and therapy for patients with CVID.
我们报告一例病例并进行文献综述，以阐明常见可变免疫缺陷（CVID）患者的许多关键特征。这些患者经常出现由多种不同微生物引起的反复感染。反复的鼻窦肺部感染可导致严重的慢性并发症，如支气管扩张，胃肠道感染可导致吸收不良。除严重感染外，CVID还与多种合并症相关，包括各种自身免疫性疾病和肿瘤。在此，我们提供一例说明性病例报告，并讨论CVID患者的主要特征和治疗方法。
