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[慢性肾盂肾炎杀菌治疗前后联合应用对氨基马尿酸-菊粉清除率测定肾功能]

[Measurement of kidney function using combined PAH-inulin clearance before and after bactericide treatment of chronic pyelonephritis].

作者信息

Möllmann R, Kraatz G, Latotzki H

出版信息

Z Gesamte Inn Med. 1975 Aug 1;30(15):509-11.

PMID:1189497
Abstract

On account of the solution of the problem, whether already after a four weeks' therapy with antibiotics in chronic progressing pyelonephritis a measurable increase of function may develop, the combined PAH-inulin-clearance was performed 35 times. 9 patients did not show a clear restriction of the clearance, wherefore in these cases a control examination was not necessary. In 10 patients of 12 an increase was present, in 7 patients a significant increase of the renal function existed after the therapy carried out. Therefore already after antibiotic impact therapy in patients with chronic pyelonephritis without provable acute episode an improvement of the function can occur, which is to be increased or kept by means of the long-term treatment.

摘要

鉴于慢性进行性肾盂肾炎患者在接受四周抗生素治疗后是否会出现可测量的功能增加这一问题,共进行了35次对氨基马尿酸-菊粉清除率联合检测。9例患者的清除率未显示明显受限,因此这些病例无需进行对照检查。12例患者中有10例出现了增加,7例患者在进行治疗后肾功能显著增加。因此,对于无明显急性发作的慢性肾盂肾炎患者,在进行抗生素冲击治疗后,肾功能即可出现改善,且可通过长期治疗进一步提高或维持。

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