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酒精性肝炎(作者译)

[Alcoholic hepatitis (author's transl)].

作者信息

Stötzner H

出版信息

Zentralbl Allg Pathol. 1975;119(1-2):27-32.

PMID:1189667
Abstract

Among 64 patients with chronic alcoholic liver damage, alcoholic hepatitis was present in 30 cases. Varying degrees of inflammation with a different high amount of polymorphonuclear leukocytes as a consistent finding, hepatocellular necrosis, fatty change in the liver epithelium, hydropic swelling of some cells, liver alcoholic hyalin, bile duct proliferation and portal edema were found to be characteristic features of alcoholic hepatitis. Hepatocellular necrosis and fatty change in the liver epithelium always occurred in alcoholic hepatitis. There was a positive association between the severity of the remaining four histological features and that of the inflammatory basic finding. The characteristic inflammatory changes were often observed to be spotty in distribution.

摘要

在64例慢性酒精性肝损伤患者中,30例存在酒精性肝炎。发现不同程度的炎症伴不同数量的多形核白细胞是一致的表现,肝细胞坏死、肝上皮细胞脂肪变性、部分细胞水样肿胀、肝酒精透明小体、胆管增生和门脉水肿是酒精性肝炎的特征性表现。肝细胞坏死和肝上皮细胞脂肪变性在酒精性肝炎中总是会出现。其余四种组织学特征的严重程度与炎症基本表现的严重程度之间存在正相关。特征性炎症改变常呈散在分布。

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