超脉冲二氧化碳激光成功用于治疗基底细胞痣综合征患者身上发现的基底细胞癌。
Ultrapulse CO2 used for the successful treatment of basal cell carcinomas found in patients with basal cell nevus syndrome.
作者信息
Nouri Keyvan, Chang Attica, Trent Jennifer T, Jiménez Gloria P
机构信息
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA.
出版信息
Dermatol Surg. 2002 Mar;28(3):287-90. doi: 10.1046/j.1524-4725.2002.01080.x.
BACKGROUND
Basal cell nevus syndrome (BCNS) is an inherited condition marked by multiple basal cell carcinomas (BCCs) associated with several other abnormalities. Various treatment modalities have been used to eradicate these tumors. However, recurrences and scarring limit their use.
OBJECTIVE
To evaluate the treatment of multiple BCCs associated with BCNS.
METHODS
We describe three cases of BCNS in which multiple BCCs were effectively treated with ultrapulse CO2 laser. Postoperative Mohs micrographic surgical sections (thin sections looking for residual tumor) verified complete histologic clearance of the tumors.
RESULTS
All three patients were effectively treated with ultrapulse CO2 laser. Minimal scarring was noted at follow-up.
CONCLUSION
Ultrapulse CO2 laser can be used to effectively treat small BCCs in low-risk areas associated with BCNS with minimal posttreatment scarring.
背景
基底细胞痣综合征（BCNS）是一种遗传性疾病，其特征为多发性基底细胞癌（BCC）并伴有其他多种异常。已采用多种治疗方式来根除这些肿瘤。然而，复发和瘢痕形成限制了它们的应用。
目的
评估与基底细胞痣综合征相关的多发性基底细胞癌的治疗方法。
方法
我们描述了3例基底细胞痣综合征患者，其中多发性基底细胞癌经超脉冲二氧化碳激光有效治疗。术后莫氏显微外科切片（用于寻找残留肿瘤的薄片）证实肿瘤在组织学上已完全清除。
结果
所有3例患者均经超脉冲二氧化碳激光有效治疗。随访时发现瘢痕形成轻微。
结论
超脉冲二氧化碳激光可用于有效治疗与基底细胞痣综合征相关的低风险区域的小基底细胞癌，且治疗后瘢痕形成轻微。
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