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抽动症的治疗。

The treatment of tics.

作者信息

Singer H S

机构信息

Departments of Neurology and Pediatrics, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Harvey 811, Baltimore, MD 21287-8811, USA.

出版信息

Curr Neurol Neurosci Rep. 2001 Mar;1(2):195-202. doi: 10.1007/s11910-001-0016-8.

DOI:10.1007/s11910-001-0016-8
PMID:11898516
Abstract

Tics are the essential component of a variety of disorders, notably Tourette syndrome. Because the mere presence of tics does not require therapeutic intervention, criteria are essential for determining a functional disability. Suggested tic-suppressing treatments have been extremely diverse, including hydrotherapy, behavioral treatments, pharmacotherapy, botulinum toxin, immunomodulatory therapy, and surgery. This manuscript reviews each of these approaches with emphasis on more recent pharmacologic trials.

摘要

抽动是多种疾病的重要组成部分,尤其是抽动秽语综合征。由于仅仅存在抽动并不需要治疗干预,因此确定功能残疾的标准至关重要。建议的抽动抑制治疗方法极为多样,包括水疗、行为治疗、药物治疗、肉毒杆菌毒素、免疫调节治疗和手术。本手稿回顾了这些方法中的每一种,并重点介绍了最近的药物试验。

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2
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Centromedian-Parafascicular Complex Deep Brain Stimulation for Tourette Syndrome: A Retrospective Study.丘脑中央中核-束旁复合体深部脑刺激治疗抽动秽语综合征:一项回顾性研究
Mayo Clin Proc. 2016 Feb;91(2):218-25. doi: 10.1016/j.mayocp.2015.11.016.
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Centromedian-parafascicular deep brain stimulation induces differential functional inhibition of the motor, associative, and limbic circuits in large animals.

本文引用的文献

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Risperidone in the treatment of Tourette syndrome: a retrospective case note study.利培酮治疗抽动秽语综合征:回顾性病历研究。
J Psychopharmacol. 1996 Jan;10(4):317-20. doi: 10.1177/026988119601000411.
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Botulinum toxin for simple motor tics: a randomized, double-blind, controlled clinical trial.肉毒杆菌毒素治疗单纯运动性抽动:一项随机、双盲、对照临床试验。
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Current issues in Tourette syndrome.抽动秽语综合征的当前问题
中央旁正中-丘脑底核深部脑刺激在大型动物中诱导运动、联合和边缘回路的功能抑制的差异。
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Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET.妥瑞氏症中多巴胺能和血清素能神经传递的机制:来自一项正电子发射断层扫描体内神经化学研究的线索
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Contemporary assessment and pharmacotherapy of Tourette syndrome.抽动秽语综合征的当代评估与药物治疗
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Mecamylamine in Tourette's syndrome: a two-year retrospective case study.美加明在抽动秽语综合征中的应用:一项为期两年的回顾性病例研究。
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Olanzapine in severe Gilles de la Tourette syndrome: a 52-week double-blind cross-over study vs. low-dose pimozide.奥氮平治疗重度抽动秽语综合征:一项为期52周的双盲交叉研究与低剂量匹莫齐特对比
J Neurol. 2000 Jun;247(6):443-6. doi: 10.1007/s004150070173.
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Botulinum toxin in the treatment of tics.肉毒杆菌毒素治疗抽动症。
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Effective open-label treatment of tourette's disorder with olanzapine.奥氮平对图雷特氏症的有效开放标签治疗。
Int Clin Psychopharmacol. 2000 Jan;15(1):23-8. doi: 10.1097/00004850-200015010-00003.
8
Tourette's syndrome improvement with pergolide in a randomized, double-blind, crossover trial.在一项随机、双盲、交叉试验中培高利特对抽动秽语综合征的改善作用
Neurology. 2000 Mar 28;54(6):1310-5. doi: 10.1212/wnl.54.6.1310.
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Ziprasidone treatment of children and adolescents with Tourette's syndrome: a pilot study.齐拉西酮治疗儿童和青少年抽动秽语综合征:一项初步研究。
J Am Acad Child Adolesc Psychiatry. 2000 Mar;39(3):292-9. doi: 10.1097/00004583-200003000-00010.
10
Tourette syndrome, associated conditions and the complexities of treatment.抽动秽语综合征、相关病症及治疗的复杂性
Brain. 2000 Mar;123 Pt 3:425-62. doi: 10.1093/brain/123.3.425.