Gilbert Donald
Movement Disorders and Tourette Syndrome Clinics, Cincinnati Children's Hospital Medical Center, OH 45229-3039, USA.
J Child Neurol. 2006 Aug;21(8):690-700. doi: 10.1177/08830738060210080401.
Tics, patterned movements distinct from stereotypies, myoclonus, and other hyperkinetic movements, are quite common in children, particularly among those with developmental and psychiatric disorders. Thus, tics can indicate the presence of atypical neurodevelopment or broader difficulties with cognition or mood. Tics are also the cardinal feature of Tourette syndrome, a childhood-onset neurobehavioral disorder characterized by a chronic inability to suppress or an urge to perform patterned, repetitive movements. Patients with Tourette syndrome most commonly have, in addition to tics, symptoms of inattention, hyperactivity, obsessiveness, or anxiety. Achieving the most effective treatment of a child with tics is contingent on proper diagnosis of the movement disorder and thorough assessment for other problems, followed by consideration of both nonpharmacologic and pharmacologic interventions for any and all symptoms interfering with the child's function and quality of life. This review focuses primarily on the diagnosis and medical treatment of tics in children and adolescents with Tourette syndrome.
抽动是一种与刻板动作、肌阵挛及其他运动亢进性动作不同的模式化动作,在儿童中相当常见,尤其是在患有发育障碍和精神疾病的儿童中。因此,抽动可能表明存在非典型神经发育或更广泛的认知或情绪问题。抽动也是抽动秽语综合征的主要特征,抽动秽语综合征是一种儿童期起病的神经行为障碍,其特征是长期无法抑制或有执行模式化、重复性动作的冲动。除了抽动外,抽动秽语综合征患者最常见的症状还有注意力不集中、多动、强迫观念或焦虑。要实现对抽动儿童的最有效治疗,取决于对运动障碍的正确诊断以及对其他问题的全面评估,随后要考虑针对任何干扰儿童功能和生活质量的症状采取非药物和药物干预措施。本综述主要关注抽动秽语综合征患儿及青少年抽动的诊断和药物治疗。