Bernardini G L, DeShaies E M
Departments of Neurology and Neurosurgery, Albany Medical Center, 47 New Scotland Avenue, MC-70, Albany, NY 12208-3479, USA.
Curr Neurol Neurosci Rep. 2001 Nov;1(6):568-76. doi: 10.1007/s11910-001-0064-0.
The acute management of primary intracerebral or aneurysmal subarachnoid hemorrhage requires a comprehensive approach involving stabilization of the patient, surgical intervention, and continued intensive care treatment of medical and neurologic complications. The are several causes of intracerebral hemorrhage (ICH), including hypertension, cerebral amyloid angiopathy, sympathomimetic drugs, and coagulopathies. More recently, use of thrombolytic agents in the treatment of acute ischemic stroke has increased the risk of ICH. Treatment of intracerebral hemorrhage is based on blood pressure control, and, in selected cases, surgical evacuation of clot. Patients with aneurysmal subarachnoid hemorrhage may experience rebleeding, symptomatic vasospasm, or hydrocephalus. Medical management in the intensive care unit with careful attention to fluid and electrolyte balance, nutrition, cardiopulmonary monitoring, and close observation for changes in the neurologic exam is vital. This review examines the diagnosis and intensive care management of patients with intracerebral or subarachnoid hemorrhage, and reviews some of the newer therapies for treatment of these disorders.
原发性脑出血或动脉瘤性蛛网膜下腔出血的急性处理需要综合方法,包括患者的稳定、手术干预以及对医学和神经并发症的持续重症监护治疗。脑出血(ICH)有多种病因,包括高血压、脑淀粉样血管病、拟交感神经药物和凝血功能障碍。最近,在急性缺血性卒中治疗中使用溶栓药物增加了脑出血的风险。脑出血的治疗基于血压控制,在特定情况下还包括手术清除血凝块。动脉瘤性蛛网膜下腔出血患者可能会发生再出血、症状性血管痉挛或脑积水。在重症监护病房进行医疗管理,密切关注液体和电解质平衡、营养、心肺监测以及对神经检查变化的密切观察至关重要。本综述探讨了脑出血或蛛网膜下腔出血患者的诊断和重症监护管理,并回顾了一些治疗这些疾病的新疗法。