Neurointensive Care Unit, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Curr Opin Crit Care. 2011 Apr;17(2):85-93. doi: 10.1097/MCC.0b013e328342f83d.
Early aggressive treatment of poor-grade subarachnoid hemorrhage patients has resulted in more favorable long-term outcomes. This article covers the aspects of neurocritical care management directed to the patient with poor-grade subarachnoid hemorrhage (Hunt and Hess 4 and 5) and outlines important prognostic features.
Immediate cardiopulmonary and neurological support, early aneurysm repair, neuromodality and multimodality monitoring under the care of neurointensivists, treatment of medical complications, prevention and appropriate management of delayed cerebral ischemia have improved long-term outcomes after poor-grade subarachnoid hemorrhage. This includes control of intracranial hypertension, optimization of cerebral perfusion pressure and cardiac hemodynamics, correction of electrolyte abnormalities, and management of complications. Global cerebral edema, acute ischemic injury seen on diffusion-weighted imaging, and early vasospasm are disease states in the poor-grade patients that require attention and further investigation. Monitoring techniques such as surface and intracortical continuous electroencephalography, brain tissue oxygen monitoring, and microdialysis may detect secondary brain injury in a potentially reversible state.
Poor-grade subarachnoid hemorrhage patients have the potential to recover and should therefore be fully resuscitated and treated aggressively with the available standards and monitoring techniques.
早期积极治疗低分级蛛网膜下腔出血患者可获得更好的长期预后。本文涵盖了针对低分级蛛网膜下腔出血(Hunt 和 Hess 分级 4 和 5 级)患者的神经重症监护管理方面,并概述了重要的预后特征。
立即进行心肺和神经支持、早期动脉瘤修复、神经重症监护下的神经调节和多模态监测、治疗医疗并发症、预防和适当处理迟发性脑缺血,这些都改善了低分级蛛网膜下腔出血患者的长期预后。这包括控制颅内压、优化脑灌注压和心输出量、纠正电解质异常以及处理并发症。弥漫加权成像上可见的全脑肿胀、急性缺血性损伤和早期血管痉挛是低分级患者需要关注和进一步研究的疾病状态。监测技术,如表面和皮质内连续脑电图、脑组织氧监测和微透析,可能会检测到潜在可逆状态下的继发性脑损伤。
低分级蛛网膜下腔出血患者有恢复的潜力,因此应充分复苏,并使用现有标准和监测技术积极治疗。