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High-dose adjuvant chemotherapy for patients with high-risk breast cancer: efficacy is still an open question.

出版信息

Clin Breast Cancer. 2000 Oct;1(3):191-2. doi: 10.1016/s1526-8209(11)70136-7.

DOI:10.1016/s1526-8209(11)70136-7
PMID:11899643
Abstract
摘要

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1
High-dose adjuvant chemotherapy for patients with high-risk breast cancer: efficacy is still an open question.高危乳腺癌患者的大剂量辅助化疗：疗效仍是一个悬而未决的问题。
Clin Breast Cancer. 2000 Oct;1(3):191-2. doi: 10.1016/s1526-8209(11)70136-7.
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Acute and late toxicity following adjuvant high-dose chemotherapy for high-risk primary operable breast cancer--a quality assessment study.高危原发性可手术乳腺癌辅助大剂量化疗后的急性和晚期毒性——一项质量评估研究
Acta Oncol. 2002;41(7-8):675-83.
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Quality of life in women with breast cancer during the first year after random assignment to adjuvant treatment with marrow-supported high-dose chemotherapy with cyclophosphamide, thiotepa, and carboplatin or tailored therapy with Fluorouracil, epirubicin, and cyclophosphamide: Scandinavian Breast Group Study 9401.随机分配接受骨髓支持的高剂量环磷酰胺、噻替派和卡铂化疗辅助治疗或氟尿嘧啶、表柔比星和环磷酰胺个体化治疗的乳腺癌女性在第一年的生活质量：斯堪的纳维亚乳腺癌研究组9401。
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Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement.高剂量化疗及造血祖细胞支持用于伴有广泛腋窝淋巴结受累的可手术乳腺癌的随机试验
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[High-dosage chemotherapy and autologous transplant of hematopoietic germ cells from peripheral blood in high-risk recurrence carcinoma of the breast (with >= or 10 involved axillary nodes at diagnosis) Preliminary results of the Solti 9301 cooperative study].[高危复发乳腺癌（诊断时腋窝淋巴结转移≥10个）外周血造血干细胞高剂量化疗及自体移植：Solti 9301合作研究的初步结果]
Sangre (Barc). 1997 Apr;42 Suppl 1:53-6.
7
Breast cancer-specific mRNA transcripts presence in peripheral blood after adjuvant chemotherapy predicts poor survival among high-risk breast cancer patients treated with high-dose chemotherapy with peripheral blood stem cell support.辅助化疗后外周血中存在乳腺癌特异性mRNA转录本预示着接受高剂量化疗及外周血干细胞支持治疗的高危乳腺癌患者生存率较低。
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High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.高剂量化疗联合造血干细胞救援治疗高危乳腺癌。
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Is radiotherapy an option for early breast cancers with complete clinical response after neoadjuvant chemotherapy?新辅助化疗后完全临床缓解的早期乳腺癌患者是否可行放疗？
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Conventional adjuvant chemotherapy with or without high-dose chemotherapy and autologous stem-cell transplantation in high-risk breast cancer.高危乳腺癌中采用或不采用大剂量化疗及自体干细胞移植的传统辅助化疗。
N Engl J Med. 2003 Jul 3;349(1):17-26. doi: 10.1056/NEJMoa030684.