Carruthers S G
London Health Sciences Centre, The University of Western Ontario.
Adv Exp Med Biol. 2001;498:119-25. doi: 10.1007/978-1-4615-1321-6_16.
In summary, the present information on treating hypertension in the diabetic overwhelmingly indicates a compelling need to lower BP to target diastolic BP of 80 mmHg or less, to be less concerned about the types of drugs used than the blood pressures achieved and the concordance with therapy and to rely on two or more antihypertensive drugs in the majority of cases. Management of the hypertensive diabetic is very cost-effective. It is clear that we must engage in total cardiovascular risk management if we are to prevent the microvascular and macrovascular complications in the hypertensive diabetic (or the diabetic hypertensive).
总之,目前关于糖尿病患者高血压治疗的信息强烈表明,迫切需要将血压降至目标舒张压80 mmHg或更低,相比于所用药物类型,更应关注所达到的血压水平以及治疗依从性,并且在大多数情况下依靠两种或更多种抗高血压药物。高血压糖尿病患者的管理具有很高的成本效益。显然,如果我们要预防高血压糖尿病患者(或糖尿病高血压患者)的微血管和大血管并发症,就必须进行全面的心血管风险管理。