Guo Xiuqing, Olson Jane M, Elston Robert C, Niu Tianhua
Division of Medical Genetics, Department of Medicine and Pediatrics, Spielberg Pediatrics Research Center, Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, Calif. 90048, USA.
Hum Hered. 2002;53(1):45-8. doi: 10.1159/000048604.
Guo and Elston [Hum Hered 1999;49:112-118] developed a linkage information content (LIC) value to measure the informativeness of a marker for identity-by-descent (IBD) sharing status of relative pairs. LIC values were derived for five types of relative pairs: full sib, half sib, grandparent-grandchild, first cousin and avuncular. In this paper, we give corrected LIC values for full sib, grandparent-grandchild, first cousin and avuncular pairs, and indicate the availability of a computer program to calculate them.
郭和埃尔斯顿[《人类遗传学》1999年；49:112 - 118]开发了一种连锁信息含量（LIC）值，用于衡量一个标记对于亲属对按血缘相同（IBD）共享状态的信息量。得出了五种亲属对类型的LIC值：全同胞、半同胞、祖孙、一级表亲和叔侄。在本文中，我们给出了全同胞、祖孙、一级表亲和叔侄对的校正LIC值，并指出了一个用于计算它们的计算机程序的可用性。
