Sillevis Smitt J H
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Huidziekten, Postbus 22.660, 1100 DD Amsterdam.
Ned Tijdschr Geneeskd. 2002 Mar 2;146(9):400-4.
Atopic dermatitis is a common skin disease with a major impact on the quality of life. The cause of this disease is unknown and the diagnosis is made using a set of diagnostic features. In very moderate cases topical treatment of the dry skin may be sufficient. In more severe cases topical treatment with corticosteroids is recommended. Dependent on the steroid used and the severity of the eczema, different application schemes and treatment methods may be used. In exceptional cases, tar derivatives, topical antibacterial compounds and non-steroidal anti-inflammatory drugs may be applied. In the near future, the limited therapeutic arsenal of topically effective substances will almost certainly be extended to include drugs such as tacrolimus and pimecrolimus with an inhibiting effect on inflammatory cytokines.
特应性皮炎是一种常见的皮肤病，对生活质量有重大影响。这种疾病的病因尚不清楚，诊断是根据一系列诊断特征进行的。在非常轻度的病例中，对干性皮肤进行局部治疗可能就足够了。在更严重的病例中，建议使用皮质类固醇进行局部治疗。根据所使用的类固醇和湿疹的严重程度，可采用不同的应用方案和治疗方法。在特殊情况下，可应用焦油衍生物、局部抗菌化合物和非甾体抗炎药。在不久的将来，局部有效物质有限的治疗手段几乎肯定会扩大，纳入对炎性细胞因子有抑制作用的药物，如他克莫司和吡美莫司。
