Yttrium-90 citrate colloid for radioisotope synovectomy.
作者信息
Bowen B M, Darracott J, Garnett E S, Tomlinson R H
出版信息
Am J Hosp Pharm. 1975 Oct;32(10):1027-30.
PMID:1190215
Abstract
The preparation of an yttrium-90 citrate colloid is described. This formulation localizes in the synovial membrane and thereby eliminates any irradiation received by extra-articular tissues. Yttrium-90 is eluted from Sr-90 bound to a sulphonic acid ion exchange resin. The colloid is prepared using a 3:1 ratio of carrier yttrium and citrate. Contamination with ionic 90Y and ionic 90Sr was less than 1 percent and 0.001 percent, respectively. In the 28 patients studied, all of the injected dose of 90Y remained in the region of the joint. Brief clinical results are presented.
摘要
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Yttrium-90 citrate colloid for radioisotope synovectomy.
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