Bakkum R S L A, Heule F
Department of Dermatology and Venereology, University Hospital Rotterdam, Dr Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.
Br J Dermatol. 2002 Feb;146(2):275-9. doi: 10.1046/j.1365-2133.2002.04578.x.
Photoallergic contact dermatitis is of importance in a proportion of photodermatoses and can be evaluated through photopatch testing.
To conduct a retrospective evaluation of photopatch tests performed in patients with suspected photodermatoses at the clinic at the University Hospital Rotterdam during a 10-year period.
During the first 5(1/2) years 44 patients were tested with a standard set of 14 allergens, and during the next 4(1/2) years 55 patients were tested with a standard set of 23 allergens.
Photocontact reactions were found in 9% and 27% of patients in the two periods, respectively. In the second period, positive reactions were mostly produced by sunscreens. The difference in the percentage of positive photopatch tests was probably caused by the difference in composition of the standard set of allergens (more sunscreens in the second period), this being the only alteration in the test procedure.
The standard set of photoallergens has to be updated periodically. Standardization of the test procedure is needed to compare the test results of different institutions.
光变应性接触性皮炎在部分光皮肤病中具有重要意义，可通过光斑贴试验进行评估。
对鹿特丹大学医院门诊10年间疑似光皮肤病患者进行的光斑贴试验进行回顾性评估。
在前5.5年中，44例患者用一套包含14种变应原的标准制剂进行检测，在接下来的4.5年中，55例患者用一套包含23种变应原的标准制剂进行检测。
两个时期分别有9%和27%的患者出现光接触反应。在第二个时期，阳性反应大多由防晒霜引起。光斑贴试验阳性率的差异可能是由于标准变应原制剂组成不同（第二个时期防晒霜更多）所致，这是检测程序中唯一的改变。
光变应原标准制剂必须定期更新。需要对检测程序进行标准化以比较不同机构的检测结果。
