Khorshid M R, Moffat D B
Anat Anz. 1975;138(1-2):69-77.
The effects of changes of water balance on the renal pelvic epithelium of the rat. The fine structure of the various epithelia which line the renal pelvis was investigated in five hydropenic rats and five rats undergoing a water diuresis. In the former, the thin epithelium which covers the outer medulla showed dilated intercellular spaces and an increased number of cytoplasmic vacuoles whereas the intercellular spaces were tightly closed and there were few vacuoles in the diuretic rats. It was considered that these changes indicate an exchange of water and solute between pelvic urine and the outer since medulla they are similar to those occurring in epithelia elsewhere which are engaged in transport of salt or water. Similar but less marked changes were found in the papillary epithelium. Changes in the transitional epithelium were similar to those which have previously been described elsewhere in the urinary tract.
水平衡变化对大鼠肾盂上皮的影响。研究了5只禁水大鼠和5只处于水利尿状态大鼠肾盂内衬的各种上皮的精细结构。在禁水大鼠中，覆盖外髓质的薄上皮细胞间间隙扩张，细胞质空泡数量增加；而在利尿大鼠中，细胞间间隙紧密闭合，空泡较少。据认为，这些变化表明肾盂尿液与外髓质之间存在水和溶质的交换，因为它们类似于其他参与盐或水转运的上皮中发生的变化。在乳头上皮中也发现了类似但不太明显的变化。移行上皮的变化与先前在泌尿道其他部位所描述的变化相似。
