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114名女性子宫肌瘤症状性肌瘤的子宫动脉栓塞治疗:肌瘤大小的缩小及女性对治疗成功的看法

Uterine artery embolisation for the treatment of symptomatic fibroids in 114 women: reduction in size of the fibroids and women's views of the success of the treatment.

作者信息

Watson G M T, Walker W J

机构信息

Department of Diagnostic Radiology, The Royal Surrey County Hospital, Guildford, UK.

出版信息

BJOG. 2002 Feb;109(2):129-35. doi: 10.1111/j.1471-0528.2002.01006.x.

Abstract

OBJECTIVE

To assess the reduction in size of fibroids following uterine artery embolisation and to analyse women's views of the success of treatment.

DESIGN

An uncontrolled case series of 114 consecutive women who underwent uterine artery embolisation for the treatment of fibroids over two years.

SETTING

The Diagnostic and Interventional Radiology Department at The Royal Surrey County Hospital, Guildford, UK.

METHODS

Bilateral uterine artery embolisation was performed for the treatment of symptomatic fibroids. Magnetic resonance imaging was carried out before and six months following embolisation. Women completed outcome questionnaires following their treatment.

MAIN OUTCOME MEASURES

The sites. imaging signal characteristics and percentage reduction in the volume of three dominant fibroids were determined from the magnetic resonance scans. Outcome was measured by questionnaire. Women were asked whether their symptoms resolved completely, improved, remained unchanged or deteriorated.

RESULTS

One hundred and sixty-five fibroids of 114 women (mean age 42) were analysed. Forty-five percent of women had complex fibroid masses and 50% had fibroids > or =8.5cm in diameter. The median reduction in the fibroid volume was 58%. The median reduction of the volume of complex fibroid masses, submucous fibroids, fibroids > or =8.5cm and fibroids with high and low signal on T2 weighted sequences were 58%, 63%, 50%, 62% and 51%, respectively. Ninety-one percent of the women's symptoms had resolved or improved following embolisation.

DISCUSSION

The majority of women were satisfied with their outcome. We have shown that uterine artery embolisation is a successful treatment for symptomatic fibroids of all types, sizes and signal characteristics.

摘要

目的

评估子宫动脉栓塞术后肌瘤大小的缩小情况,并分析女性对治疗成功的看法。

设计

一项非对照病例系列研究,连续纳入114名在两年内接受子宫动脉栓塞治疗肌瘤的女性。

地点

英国吉尔福德皇家萨里郡医院诊断与介入放射科。

方法

对有症状的肌瘤进行双侧子宫动脉栓塞治疗。栓塞前及栓塞后6个月进行磁共振成像检查。女性在治疗后完成结局调查问卷。

主要结局指标

从磁共振扫描中确定三个主要肌瘤的部位、成像信号特征及体积缩小百分比。通过问卷测量结局。询问女性其症状是完全缓解、改善、不变还是恶化。

结果

分析了114名女性(平均年龄42岁)的165个肌瘤。45%的女性有复杂肌瘤团块,50%的女性肌瘤直径≥8.5cm。肌瘤体积的中位数缩小了58%。复杂肌瘤团块、黏膜下肌瘤、直径≥8.5cm的肌瘤以及在T2加权序列上有高信号和低信号的肌瘤体积的中位数缩小分别为58%、63%、50%、62%和51%。91%的女性在栓塞后症状得到缓解或改善。

讨论

大多数女性对其结局满意。我们已表明子宫动脉栓塞术是治疗所有类型、大小及信号特征的有症状肌瘤的成功方法。

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