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儿童活体肝移植

Living-donor liver transplantation in children.

作者信息

Emre Sukru

机构信息

The Recanati/Miller Transplantation Institute,The Mount Sinai School of Medicine, New York, New York 10029, USA.

出版信息

Pediatr Transplant. 2002 Feb;6(1):43-6. doi: 10.1034/j.1399-3046.2002.1r072.x.

Abstract

With evolution of surgical technique, advances in immunosuppression, and better understanding of pre- and post-operative care, the 1-yr survival rate after liver transplantation in children has reached 85-90%. As a result, a greater number of patients have been listed for transplantation and waiting times have lengthened. Innovative techniques such as reduced-size, split, and living-donor liver transplantation are being applied more often to decrease long waiting times and reduce associated morbidity and mortality. In this review, living donor liver transplantation in pediatrics is described. Special issues, such as donor and recipient selection, surgical procedures in donors and recipients, and ethical issues, are discussed.

摘要

随着手术技术的发展、免疫抑制的进步以及对术前和术后护理的更深入理解,儿童肝移植术后1年生存率已达到85% - 90%。因此,有更多患者被列入移植名单,等待时间也延长了。诸如减体积肝移植、劈离式肝移植和活体供肝肝移植等创新技术正被更频繁地应用,以减少长时间等待并降低相关的发病率和死亡率。在本综述中,将描述儿科活体供肝肝移植。还将讨论一些特殊问题,如供体和受体的选择、供体和受体的手术程序以及伦理问题。

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