Henkin R I, Larson A L, Powell R D
Ann Otol Rhinol Laryngol. 1975 Sep-Oct;84(5 Pt 1):672-82. doi: 10.1177/000348947508400519.
Hypogeusia, with or without dysgenusia, and hyposmia, with or without dysosmia, followed an influenzal-like infection in 87 of 143 consecutive patients who presented at the Taste and Smell Clinic at the NIH with taste and smell abnormalities. Findings in this disease included pale nasal mucous membranes with marked patency of the nasal airway, a postive Rudolph sign, elevated detection and recognition thresholds for several tastants and odorants, disruption of the pore region of the tast dub observed on electron microscopy and infiltration of the upper lamina propria of the nasal mucous membrane wih chronic inflammatory cells observed on light microscopy. These findings, taken together, are relatively specific for the diagnosis of this surprisingly common disorder.
在国立卫生研究院味觉与嗅觉门诊就诊的143例有味觉和嗅觉异常的连续患者中，87例在类似流感的感染后出现味觉减退（伴或不伴有味觉发育异常）和嗅觉减退（伴或不伴有嗅觉发育异常）。该疾病的表现包括鼻黏膜苍白、鼻腔气道明显通畅、鲁道夫征阳性、多种味觉剂和嗅觉剂的检测和识别阈值升高、电子显微镜下观察到味觉小体孔区域破坏以及光学显微镜下观察到鼻黏膜固有层上层有慢性炎症细胞浸润。综合这些发现，对于诊断这种出人意料地常见的疾病具有相对特异性。
