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[会议论文:大鼠胎儿培养肝细胞中皮质醇依赖性糖原储存及对胰岛素和胰高血糖素的反应(作者译)]

[Proceedings: Cortisol-dependent glycogen storage and responses to insulin and glucagon in rat fetal cultured hepatocytes (author's transl)].

作者信息

Plas C

出版信息

Ann Endocrinol (Paris). 1975 Jan-Feb;36(1):40-1.

PMID:1190713
Abstract

It has been shown that in primary cultures of rat fetal hepatocytes cortisol induces the development of glycogen storage ability. Cortisol has also a permissive effect in insulin action on the development of the glycogen synthetic pathway. However the regulation of glycogenolytic pathway by glucagon, which is present before any significant amount of glycogen storage, is not cortisol dependent.

摘要

研究表明,在大鼠胎儿肝细胞的原代培养中,皮质醇可诱导糖原储存能力的发展。皮质醇对胰岛素作用于糖原合成途径的发展也有允许作用。然而,在任何大量糖原储存出现之前就存在的胰高血糖素对糖原分解途径的调节并不依赖于皮质醇。

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