Thomachot L, Viviand X, Boyadjiev I, Vialet R, Martin C
Department of Intensive Care and Trauma Center, Marseilles School of Medicine, Hôpital Nord, 13915 Marseille Cedex 20, France.
Intensive Care Med. 2002 Feb;28(2):147-53. doi: 10.1007/s00134-001-1193-2. Epub 2002 Jan 12.
To determine whether the combination with a new device (Booster ) for active humidification improves the efficacy of a hydrophobic heat and moisture exchanger (HME).
Prospective, interventional study in the ICU of a university hospital.
Consecutive patients requiring controlled mechanical ventilation
Patients were ventilated with a HME, and a Booster was added for 96 h to the ventilatory circuit.
During the inspiration phase the following factors were measured: peak and mean airway pressures, maximal (beginning of inspiration), minimal (end of inspiration), and mean values of temperature of inspired gases, and relative and absolute humidity of inspired gases. Microbiological samples were obtained from the Booster, the ventilator side of the HME, and the tracheal secretions on days 1 and 4. Minimal and mean temperatures were increased as soon as the Booster was used and this increase was maintained for 96 h until the Booster was withdrawn. Then the temperature returned to baseline values. Absolute humidity values followed the same course. There was also some indirect evidence of very little, if any, changes in the HME resistance. The ventilatory side of the HMEs remained sterile in each patient, and the Booster was colonized by the same bacteria as those in the tracheal secretions.
Adding the Booster to a hydrophobic HME improved the heat and water preservation of ventilatory gas.
确定与一种用于主动湿化的新设备(增强器)联合使用是否能提高疏水型热湿交换器(HME)的效能。
在一所大学医院的重症监护病房进行的前瞻性干预性研究。
连续的需要控制性机械通气的患者
患者使用HME进行通气,并在通气回路中添加增强器96小时。
在吸气阶段测量以下因素:气道峰压和平均压、吸入气体温度的最大值(吸气开始时)、最小值(吸气结束时)和平均值,以及吸入气体的相对湿度和绝对湿度。在第1天和第4天从增强器、HME的通气机侧以及气管分泌物中获取微生物样本。一旦使用增强器,最低温度和平均温度立即升高,并且这种升高持续96小时,直到撤掉增强器。然后温度恢复到基线值。绝对湿度值也遵循相同的变化过程。也有一些间接证据表明HME阻力即使有变化也非常小。每位患者HME的通气机侧均保持无菌,增强器被与气管分泌物中相同的细菌定植。
在疏水型HME上添加增强器可改善通气气体的热和水的保持。