Terayama N, Matsui O, Gabata T, Kobayashi S, Sanada J, Ueda K, Kadoya M, Kawamori Y
Department of Radiology, Kanazawa University School of Medicine, Japan.
Cardiovasc Intervent Radiol. 2001 Nov-Dec;24(6):383-7. doi: 10.1007/s00270-001-0070-2. Epub 2001 Nov 8.
After transcatheter arterial embolization (TAE) with iodized oil (Lipiodol), a relatively dense accumulation of Lipiodol is often seen in the nontumorous liver adjacent to a hypervascular hepatocellular carcinoma (HCC) nodule. We compared this phenomenon with the findings obtained with single-level dynamic CT during hepatic arteriography (SLDCTHA) and presumed its possible mechanism.
Fifty-six patients with HCC underwent hepatic angiography including SLDCTHA followed by segmental or subsegmental TAE with a mixture of an anticancer drug and Lipiodol. We compared the drainage area of the HCC depicted on SLDCTHA with the Lipiodol accumulation in the nontumorous liver adjacent to the HCC on CT after TAE (LpCT).
In 26 of the 56 patients, a definite corona enhancement around the HCC, suggesting the drainage of blood from the tumor into the surrounding liver parenchyma, was seen on the late phase of SLDCTHA. In 17 of these 26 patients (65.4%), LpCT showed a more intense accumulation of Lipiodol in the nontumorous liver adjacent to the HCC that corresponded to the drainage area revealed on SLDCTHA.
The drainage of blood from the HCC was considered to be a possible mechanism of the accumulation of Lipiodol in the nontumorous liver adjacent to the HCC.
经导管动脉栓塞术（TAE）使用碘化油（碘油）后，在高血供肝细胞癌（HCC）结节附近的非肿瘤性肝脏中常可见到相对密集的碘油聚集。我们将这种现象与肝动脉造影期间单层动态CT（SLDCTHA）的结果进行了比较，并推测了其可能的机制。
56例HCC患者接受了包括SLDCTHA在内的肝血管造影，随后用抗癌药物和碘油的混合物进行节段性或亚节段性TAE。我们将SLDCTHA上显示的HCC引流区域与TAE后CT上HCC附近非肿瘤性肝脏中的碘油聚集情况（LpCT）进行了比较。
56例患者中有26例在SLDCTHA晚期可见HCC周围有明确的晕状强化，提示肿瘤血液引流至周围肝实质。在这26例患者中的17例（65.4%），LpCT显示HCC附近非肿瘤性肝脏中碘油聚集更强烈，且与SLDCTHA上显示的引流区域相对应。
HCC的血液引流被认为是HCC附近非肿瘤性肝脏中碘油聚集的一种可能机制。
