Byers P D, Roper B A, Glennie B
Ann Rheum Dis. 1975 Aug;34(4):298-302. doi: 10.1136/ard.34.4.298.
Using clinical, radiological, and morbid anatomical data about patients with arthritis of the hip and their femoral heads resected during total hip replacement, an attempt has been made first, to classify patients and femoral heads by a cluster analysis technique, and secondly and more realistically, to use existing clinical and radiological classification as a basis for seeking discriminating features in the data from the femoral head. Both types of analysis failed to give results, and led to a conclusion that arthritis of the hip is a spectrum of disease. This may not pose problems to the clinician, but it does to the investigator studying the pathogenesis of osteoarthrosis. This problem is briefly discussed.
利用有关髋关节关节炎患者及其在全髋关节置换术中切除的股骨头的临床、放射学和病理解剖学数据,首先尝试通过聚类分析技术对患者和股骨头进行分类,其次更实际地是,将现有的临床和放射学分类作为基础,以寻找股骨头数据中的鉴别特征。这两种分析均未得出结果,从而得出结论:髋关节关节炎是一系列疾病。这对临床医生可能不成问题,但对研究骨关节炎发病机制的研究者而言却是个问题。本文对此问题进行了简要讨论。