Yool Andrea J, Weinstein Alan M
Department of Physiology, University of Arizona College of Medicine, Tucson, Arizona 85724-5051, USA.
News Physiol Sci. 2002 Apr;17:68-72. doi: 10.1152/nips.01372.2001.
Mammalian aquaporins are part of the diverse major intrinsic protein family of water and solute channels. Intriguing links exist in structural and functional properties between aquaporins and ion channels. A novel role for aquaporin-1 as a gated ion channel reshapes our current views of this ancient family of transmembrane channel proteins.