Van Acker E, De Potter P
Unité d'Oncologie Oculaire, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Bruxelles, Belgique.
J Fr Ophtalmol. 2001 Dec;24(10):1067-73.
To examine the incidence of orbital complications in patients who underwent primary placement of a porous polyethylene implant (Medpor) after enucleation.
Prospective non randomized case series of 75 consecutive patients in whom a porous polyethylene (PP) spherical implant wrapped with homologous sclera was implanted after enucleation.
The mean age at the time of enucleation was 42.7 years (range, 1.4 to 80 years). The histopathological diagnoses after enucleation included uveal melanoma in 28 patients, retinoblastoma in 11 patients, phthisis bulbi in 23 patients, neovascular glaucoma in 5 patients, endophthalmitis in 3 patients, ruptured traumatic globe in 2 patients, microphthalmos in two patients, and medulloepithelioma in one patient. Thirty-four patients (45%) had had prior ocular surgery. The prosthesis was fitted after a mean interval of 4.5 weeks (range, 3 to 10 weeks). After a mean follow-up of 20 months (range, 3 to 33 months), there was one case (1%) of conjunctival dehiscence with material exposure secondary to massive postoperative orbital hemorrhage 2 weeks after enucleation. There was no case of orbital cellulitis, implant extrusion, or significant inflammatory response. No PP implant was drilled for peg placement. DISCUSSION-CONCLUSIONS: The anteriorly wrapped porous polyethylene orbital (Medpor) sphere appears to be well tolerated by all age groups with no major complication in primary implantation after enucleation.
研究眼球摘除术后初次植入多孔聚乙烯植入物（Medpor）的患者眼眶并发症的发生率。
对75例连续患者进行前瞻性非随机病例系列研究，这些患者在眼球摘除术后植入了包裹同种异体巩膜的多孔聚乙烯（PP）球形植入物。
眼球摘除时的平均年龄为42.7岁（范围1.4至80岁）。眼球摘除后的组织病理学诊断包括28例葡萄膜黑色素瘤、11例视网膜母细胞瘤、23例眼球痨、5例新生血管性青光眼、3例眼内炎、2例眼球破裂伤、2例小眼球和1例髓上皮瘤。34例患者（45%）曾接受过眼部手术。平均间隔4.5周（范围3至10周）后安装义眼。平均随访20个月（范围3至33个月），有1例（1%）在眼球摘除术后2周因大量术后眼眶出血导致结膜裂开并伴有材料暴露。无眼眶蜂窝织炎、植入物挤出或明显炎症反应病例。未为安装栓钉而对PP植入物进行钻孔。讨论 - 结论：前部包裹的多孔聚乙烯眼眶（Medpor）球体似乎在所有年龄组中耐受性良好，眼球摘除术后初次植入时无 major complication。（这里“major complication”直译为“主要并发症”，结合前文推测是指重大并发症，可根据实际情况调整表述）
