[D，L-1,4-二溴-1,4-二脱氧-2,3-丁二醇生物作用的一些特性]
[Some characteristics of the biological action of D, L-1,4-dibromo-1,4-dideoxy-2,3-butanediol].
作者信息
Miuller N R, Remizov A L, Belogorodskiĭ V V, Filov V A
出版信息
Farmakol Toksikol. 1975 Sep-Oct;38(5):590-1.
PMID:1191387
Abstract
In tests conducted on mice and rats with transplantable tumours the antineoplastic activity of the racemic agent D, L-1,4-dibromo-1, 4-didesoxy-2, 3-butandiol is shown. With chronic administration of the drug in subtherapeutic and therapeutic doses a higher leucocytes count was in evidence in the blood of the animals with and without tumours.
摘要
在对患有可移植肿瘤的小鼠和大鼠进行的试验中，显示出消旋体D，L-1,4-二溴-1,4-二脱氧-2,3-丁二醇的抗肿瘤活性。以亚治疗剂量和治疗剂量长期给药该药物时，有肿瘤和无肿瘤动物血液中的白细胞计数均较高。
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