人乳腺癌分泌免疫反应性降钙素。
Secretion of immunoreactive calcitonin by human breast carcinomas.
作者信息
Coombes R C, Easty G C, Detre S I, Hillyard C J, Stevens U, Girgis S I, Galante L S, Heywood L, Macintyre I, Neville A M
出版信息
Br Med J. 1975 Oct 25;4(5990):197-9. doi: 10.1136/bmj.4.5990.197.
Abstract
Twenty-three out of 28 patients with metastatic breast carcinoma and one out of 13 patients with localised disease had raised levels of plasma immunoreactive calcitonin. Monolayer cultures of breast carcinomas maintained for up to 10 weeks released immunoreactive calcitonin, and a primary breast carcinoma passaged in "nude" mice for over a year contained material immunologically and chromatographically resembling the monomeric form of human calcitonin. These studies indicate that breast carcinomas can produce calcitonin and that plasma calcitonin measurements may be useful in staging patients with breast carcinomas.
摘要
28例转移性乳腺癌患者中有23例，13例局限性疾病患者中有1例血浆免疫反应性降钙素水平升高。乳腺癌单层培养物维持长达10周可释放免疫反应性降钙素，一株在“裸”鼠体内传代一年以上的原发性乳腺癌含有在免疫学和色谱学上与人降钙素单体形式相似的物质。这些研究表明乳腺癌可产生降钙素，血浆降钙素检测可能有助于乳腺癌患者的分期。
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本文引用的文献
1
IDENTIFICATION OF INSULIN AND GLUGACON IN A BRONCHOGENIC METASTASIS.支气管源性转移灶中胰岛素和胰高血糖素的鉴定
J Clin Endocrinol Metab. 1964 Sep;24:823-31. doi: 10.1210/jcem-24-9-823.
2
Evaluation of carcinoembryonic antigen in human mammary carcinoma.
J Natl Cancer Inst. 1973 Oct;51(4):1119-22. doi: 10.1093/jnci/51.4.1119.
3
Concentrations of calcitonin and catecholamines in pheochromocytomas, a mucosal neuroma and medullary thyroid carcinoma.嗜铬细胞瘤、黏膜神经瘤和甲状腺髓样癌中降钙素和儿茶酚胺的浓度。
J Clin Endocrinol Metab. 1973 Aug;37(2):297-307. doi: 10.1210/jcem-37-2-297.
4
A radioimmunoassay which specifically measures human chorionic gonadotropin in the presence of human luteinizing hormone.一种在人促黄体生成素存在的情况下特异性测量人绒毛膜促性腺激素的放射免疫分析方法。
Am J Obstet Gynecol. 1972 Jul 15;113(6):751-8. doi: 10.1016/0002-9378(72)90553-4.
5
Evidence for a pro-calcitonin.降钙素原的证据。
Biochem Biophys Res Commun. 1974 Oct 8;60(3):1134-40. doi: 10.1016/0006-291x(74)90430-6.
6
Radio-immunoassay of casein in the serum of normal subjects and of patients with various malignancies.
Eur J Cancer (1965). 1974 Nov;10(11):725-30. doi: 10.1016/0014-2964(74)90111-x.
7
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N Engl J Med. 1974 May 16;290(20):1122-4. doi: 10.1056/NEJM197405162902007.
8
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