Evans Robert D, Trites James D, Cochrane Robert L
Elanco Animal Health, Greenfield, IN 46140, USA.
Avian Dis. 2002 Jan-Mar;46(1):208-14. doi: 10.1637/0005-2086(2002)046[0208:FEOTPI]2.0.CO;2.
Mycoplasma gallisepticum infection results in numerous clinical signs including a reduction in egg production in laying chickens. Attempts to prevent mycoplasmosis have included vaccination with both killed and attenuated live M. gallisepticum strains. Live vaccines provide reduction in clinical signs and have been shown to replace indigenous strains when used in a consistent program for several placements. Antibiotic therapy is another option for controlling losses associated with mycoplasmosis. Therapeutic antibiotics with activity against mycoplasma approved for use in poultry include tetracyclines and tylosin. These drugs also are approved for feed efficiency when administered in the feed at levels below the therapeutic index for mycoplasma. The data presented here suggest that birds vaccinated with the live 6/85 strain of M. gallisepticum and then fed tylosin, at the approved level for feed efficiency, exhibit a serologic vaccine response similar to that of unmedicated birds but show improved feed efficiency.
鸡毒支原体感染会导致多种临床症状，包括蛋鸡产蛋量下降。预防支原体病的措施包括使用灭活和减毒的鸡毒支原体菌株进行疫苗接种。活疫苗可减轻临床症状，并且在连续几个批次的鸡群中持续使用时，已被证明能够替代本土菌株。抗生素治疗是控制与支原体病相关损失的另一种选择。批准用于家禽的对支原体有活性的治疗性抗生素包括四环素和泰乐菌素。当以低于支原体治疗指数的水平添加到饲料中时，这些药物也被批准用于提高饲料效率。此处呈现的数据表明，接种了鸡毒支原体活6/85菌株然后以批准的饲料效率水平饲喂泰乐菌素的鸡，其血清学疫苗反应与未用药的鸡相似，但饲料效率有所提高。
