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短暂性新生儿低血糖——对神经发育结局的长期影响。

Transient neonatal hypoglycemia--long-term effects on neurodevelopmental outcome.

作者信息

Dalgiç Nazan, Ergenekon Ebru, Soysal Sebnem, Koç Esin, Atalay Yildiz, Gücüyener Kivilcim

机构信息

Department of Neonatology, Faculty of Medicine, Gazi University, Ankara, Turkey.

出版信息

J Pediatr Endocrinol Metab. 2002 Mar;15(3):319-24. doi: 10.1515/jpem.2002.15.3.319.

DOI:10.1515/jpem.2002.15.3.319
PMID:11924935
Abstract

OBJECTIVE

To investigate the frequency, etiology and consequences of neonatal hypoglycemia.

STUDY DESIGN

Ninety-four infants admitted to Gazi University Hospital neonatal intensive care unit for hypoglycemia (blood glucose <2.2 mmol/l 140 mg/dl]) over the past 5 years were identified and investigated with regard to cause, duration of treatment and neurological outcome.

RESULTS

The frequency of neonatal hypoglycemia in our unit was 94/1,023 (9.18%). Twelve infants with hypoglycemia were small for gestational age (SGA), 55 were appropriate for gestational age (AGA), and 27 were large for gestational age (LGA). The cause of the hypoglycemia was not identified in 53 infants. SGA infants required the longest duration of i.v. glucose infusion. Forty-eight patients received psychometric evaluation, one patient showed a language deficit and two patients showed motor deficits.

CONCLUSION

Neonatal hypoglycemia is a dangerous condition for its acute and chronic complications, and may be observed in infants with no clear risk factors. However, if acted upon early, these complications are preventable with mostly very simple measures.

摘要

目的

探讨新生儿低血糖的发生率、病因及后果。

研究设计

确定过去5年因低血糖(血糖<2.2 mmol/L[140 mg/dl])入住加齐大学医院新生儿重症监护病房的94例婴儿,并对其病因、治疗持续时间和神经学结局进行调查。

结果

我们科室新生儿低血糖的发生率为94/1023(9.18%)。12例低血糖婴儿为小于胎龄儿(SGA),55例为适于胎龄儿(AGA),27例为大于胎龄儿(LGA)。53例婴儿的低血糖病因未明确。SGA婴儿静脉输注葡萄糖的持续时间最长。48例患者接受了心理测评,1例患者有语言缺陷,2例患者有运动缺陷。

结论

新生儿低血糖因其急性和慢性并发症而成为一种危险状况,在无明确危险因素的婴儿中也可能出现。然而,如果早期采取行动,这些并发症大多可用非常简单的措施预防。

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