Tajima Yutaka
Clinical Laboratory, Saga Medical School Hospital, Saga 849-8501.
Rinsho Byori. 2002 Feb;50(2):133-9.
The case of a male patient suffering from chronic normal pressure hydrocephalus is outlined. Antidepressant and pravastatin were administered because of the patient's abulia and hypercholesterolemia, but neuroleptic malignant syndrome-like conditions developed. All physicians should suppose the occurrence of such an "unexpected drug-interaction" in any case. The author considered that a good sense of careful discernment and rapid reference system of medical information are "essential tools" for clinical management.
本文概述了一名患有慢性常压脑积水的男性患者的病例。由于患者存在意志缺失和高胆固醇血症,给予了抗抑郁药和普伐他汀治疗,但出现了类神经阻滞剂恶性综合征的情况。在任何情况下,所有医生都应考虑到这种“意外药物相互作用”的发生。作者认为,敏锐的审慎洞察力和快速的医学信息参考系统是临床管理的“必备工具”。