Kobashi Yoshihiro, Okimoto Niro, Hara Yoshihito, Matsushima Toshiharu
Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kawasaki Hospital, Nakasange 2-1-80, Okayama, Japan.
Nihon Kokyuki Gakkai Zasshi. 2002 Jan;40(1):35-9.
A 76-year-old woman was admitted to our hospital because of an abnormal shadow on chest radiography and a suspected familial prevalence of pulmonary tuberculosis. Her son had previously been admitted to our hospital with pulmonary tuberculosis and tuberculous pleuritis. In the present case, a diagnosis of pulmonary tuberculosis and atypical pulmonary mycobacteriosis was made on the basis of detection of both Mycobacterium tuberculosis and M. intracellulare several times in a sputum culture of anti-fast bacilli. Restriction fragment length polymorphism (RFLP) analysis was then performed for both the woman and her son. The RFLP analysis revealed the same pattern in both mother and son, and confirmed that this was a case of mixed pulmonary infection passed from son to mother.
一名76岁女性因胸部X线片出现异常阴影以及疑似肺结核家族聚集性而入住我院。她的儿子此前因肺结核和结核性胸膜炎入住我院。在本病例中，根据抗酸杆菌痰培养多次检测到结核分枝杆菌和胞内分枝杆菌，诊断为肺结核和非典型肺分枝杆菌病。然后对该女性及其儿子进行了限制性片段长度多态性（RFLP）分析。RFLP分析显示母子二人的模式相同，证实这是一例由儿子传染给母亲的混合肺部感染病例。
