Tanaka Yuichiro, Kitahara Kenji, Nakadomari Satoshi, Kumegawa Koichi, Umahara Takahiko
Department of Ophthalmology, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan.
Nippon Ganka Gakkai Zasshi. 2002 Mar;106(3):154-61.
To localize the lesions associated with cerebral achromatopsia.
We examined 20 patients with homonymous hemianopsia caused by cerebral infarction(17 men and 3 women aged 49 to 81 years; mean age, 65.1 years). Ishihara plates, standard pseudoisochromatic plates(part 2) and the panel D-15 test were used to examine color perception. Color matching tasks and color naming tasks were used to test color recognition. We tried to apply functional magnetic resonance imaging(fMRI) to lesion analysis in the brain.
Cerebral achromatopsia was diagnosed in four patients. The analysis showed that lesions in the infracalcarine area(Brodmann's area 18 and 19) were associated with cerebral achromatopsia. Additionally, the lesions associated with failure of the panel D-15(PD-15) test were located more anterior than the lesions associated with failure of Ishihara plates.
We show evidence that lesions in the anterio-ventral temporo-occipital area are associated with cerebral achromatopsia. This result is in accord with past observations(autopsy, fMRI and positron emission tomography).
定位与脑性全色盲相关的病变。
我们检查了20例因脑梗死导致同向偏盲的患者（17名男性和3名女性，年龄49至81岁；平均年龄65.1岁）。使用石原氏色盲测试图、标准假同色图（第2部分）和D-15色盘测试来检查颜色感知。使用颜色匹配任务和颜色命名任务来测试颜色识别。我们尝试将功能磁共振成像（fMRI）应用于脑部病变分析。
4例患者被诊断为脑性全色盲。分析表明，距状裂下区（布罗德曼区18和19）的病变与脑性全色盲相关。此外，与D-15色盘（PD-15）测试失败相关的病变比与石原氏色盲测试图失败相关的病变位置更靠前。
我们有证据表明，前腹侧颞枕区的病变与脑性全色盲相关。这一结果与过去的观察结果（尸检、fMRI和正电子发射断层扫描）一致。
