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[呼吸道合胞病毒预防指南。更新版]

[Guidelines for respiratory syncytial virus prophylaxis. An update].

作者信息

Carbonell-Estrany X, Quero Jiménez J

机构信息

Instituto Clínico de Ginecología, Obstetricia y Neonatología, Unidad Integrada de Pediatría, Hospital Clínic, Barcelona, Spain.

出版信息

An Esp Pediatr. 2002 Apr;56(4):334-6.

Abstract

Epidemiological studies performed by the IRIS study group in the last two respiratory syncytial virus (RSV) seasons found that the hospitalization rates for RSV in premature infants born before or in week 32 of gestation were 13.4 % and 13.1 %, respectively. Of these, 18 % and 25 % of the infants were admitted to the intensive care unit. Currently available information demonstrates the efficacy of RSV monoclonal antibodies (palivizumab) and the absence of major adverse effects. To date, there are no data that indicate the need to modify the guidelines for RSV prophylaxis in premature infants published in 2000.

摘要

IRIS研究小组在过去两个呼吸道合胞病毒(RSV)流行季节进行的流行病学研究发现,妊娠32周之前或第32周出生的早产儿中,RSV的住院率分别为13.4%和13.1%。其中,18%和25%的婴儿被收入重症监护病房。目前可得的信息表明RSV单克隆抗体(帕利珠单抗)有效且无重大不良反应。迄今为止,尚无数据表明需要修改2000年发布的早产儿RSV预防指南。

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