Drzewoski J, Saryusz-Wolska M, Czupryniak L
Klinika Chorób Przewodu Pokarmowego i Przemiany Materii IMW AM w Łodzi.
Pol Arch Med Wewn. 2001 Sep;106(3):787-91.
Recent epidemiologic studies show increasing "epidemic" of diabetes mellitus throughout the world. Reliable data on diabetes prevalence in Poland are scarce. Therefore Polish Ministry of Health initiated a programme aiming at gathering substantial amount of epidemiologic data on the prevalence of diabetes and other metabolic disorders. The aim of the present study was to evaluate the prevalence of diabetes, obesity and lipid disorders in a well-defined urban population aged 35 and over. The study subjects were 6000 randomly chosen inhabitants of the Central District of Lodz. All were invitated to participate in the study by mail. Every participant underwent full medical examination, with body mass index (BMI) calculation, and blood pressure as well as waist-to-hip ratio measurements. Serum total, LDL and HDL cholesterol and triglycerides were assessed. In non-diabetes subjects oral glucose tolerance test (75 g) (OGTT) according to WHO protocol was performed unless their fasting capillary blood glucose exceeded 8 mmol/l. In selected subjects serum samples were stored for future insulin and C-peptide assays. 2018 persons took part in the study (response rate 33.6%), including 1217 (60.3%) women and 801 men (39.7%), mean age 58.2 years. 179 (8.9%) persons claimed to have been diagnosed with diabetes previously (8.9%). OGTT was performed in 1574 subjects. Impaired glucose tolerance (IGT) was found in 342 (17.0%), and diabetes in 138 (6.8%) subjects. Total diabetes prevalence reached therefore 15.7%. Excessive body weight (BMI > or = 25 kg/m2) was noted in 806 (39.9%), and obesity (BMI > or = 30 kg/m2) in 626 (31.0%) persons. Total cholesterol > 5.2 mmol/l was observed in 1170 (58.0%), LDL-cholesterol > 3.5 mmol/l in 734 (36.4%), cholesterol HDL < 0.9 mmol/l in 953 (47.2%), and triglycerides > 1.7 mmol/l in 1392 osób (69.0%) subjects. In conclusion, high prevalence of known and unknown diabetes together with other metabolic disorders is strikingly high in adult urban population, which in all may require effective implementation of specific nationwide prevention programmes.
近期的流行病学研究表明，糖尿病在全球范围内呈“流行”趋势且日益严重。波兰有关糖尿病患病率的可靠数据匮乏。因此，波兰卫生部启动了一项计划，旨在收集大量有关糖尿病及其他代谢紊乱患病率的流行病学数据。本研究的目的是评估35岁及以上特定城市人群中糖尿病、肥胖症和脂质紊乱的患病率。研究对象为罗兹市中心区随机选取的6000名居民。所有人均通过邮件邀请参与研究。每位参与者都接受了全面的医学检查，计算体重指数（BMI），测量血压以及腰臀比。评估血清总胆固醇、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇和甘油三酯水平。在非糖尿病受试者中，除非其空腹毛细血管血糖超过8 mmol/l，否则按照世界卫生组织的方案进行口服葡萄糖耐量试验（75 g）（OGTT）。在部分受试者中储存血清样本以备将来进行胰岛素和C肽检测。2018人参与了研究（应答率为33.6%），其中包括1217名女性（60.3%）和801名男性（39.7%），平均年龄58.2岁。179人（8.9%）声称之前已被诊断患有糖尿病（8.9%）。1574名受试者进行了OGTT。342人（17.0%）发现糖耐量受损（IGT），糖尿病患者138人（6.8%）。因此，糖尿病总患病率达到15.7%。806人（39.9%）体重超标（BMI≥25 kg/m²），626人（31.0%）患有肥胖症（BMI≥30 kg/m²）。1170人（58.0%）总胆固醇>5.2 mmol/l，734人（36.4%）低密度脂蛋白胆固醇>3.5 mmol/l，953人（47.2%）高密度脂蛋白胆固醇<0.9 mmol/l，1392人（69.0%）甘油三酯>1.7 mmol/l。总之，在成年城市人群中，已知和未知糖尿病以及其他代谢紊乱的患病率极高，这可能总体上需要有效实施特定的全国性预防计划。
