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[与角闪岩开采和加工相关的粉尘暴露与癌症风险]

[Dust exposure and cancer risk associated with amphibolite mining and processing].

作者信息

Woźniak H, Wiecek E, Bielichowska-Cybula G, Opalska B

机构信息

Zakładu Zagrozeń Chemicznych i Pyłowych Pracownia Aerozoli i Mikroklimatu Instytutu Medycyny Pracy im. prof. J. Nofera w Łodzi.

出版信息

Med Pr. 2001;52(6):437-43.

Abstract

Mining and processing of amphibolite is associated with workers' exposure to dust containing asbestos minerals (actinolite, tremolite) and with the presence of respirable fibers, i.e. small particles above 5 microns long and below 3 microns in diameter (with length-to-diameter ratio higher than 3:1). Results of epidemiological and laboratory studies show that such dust may be responsible for the development of cancer in dust-exposed people. This work reports the measurement results of concentrations of total dust, respirable fibers and mineral composition of samples collected in plant mining and processing amphibolite rock. Based on the results, cumulated exposure was calculated for the 10-, 20- and 30-year exposure periods. The cumulated exposure was classified into two categories: 0.1-1.0 f/cm3 years and 1.0-10 f/cm3. x years. It has been found that mining and processing of amphibolite is associated with increased risk of death from mesothelioma--11.2 x 10(-5) (crushers--10 years of exposure) to 240.0 x 10(-5) (miners--30 years of exposure). The risk of excessive mortality from lung cancer was not high (below 1. x 10(-4)) for all workplaces and periods of exposure.

摘要

角闪岩的开采和加工会使工人接触到含有石棉矿物(阳起石、透闪石)的粉尘以及可吸入纤维,即可吸入的纤维是指长度超过5微米且直径小于3微米的小颗粒(长径比高于3:1)。流行病学和实验室研究结果表明,此类粉尘可能导致接触粉尘人群患癌。本文报告了在角闪岩开采和加工工厂采集的样本中总粉尘浓度、可吸入纤维浓度及矿物成分的测量结果。基于这些结果,计算了10年、20年和30年暴露期的累积暴露量。累积暴露量分为两类:0.1 - 1.0 f/cm³·年和1.0 - 10 f/cm³·x年。研究发现,角闪岩的开采和加工与间皮瘤死亡风险增加有关——从11.2×10⁻⁵(破碎机工人——10年暴露)到240.0×10⁻⁵(矿工——30年暴露)。在所有工作场所和暴露期,肺癌的超额死亡风险都不高(低于1.×10⁻⁴)。

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