Sonesson Anna K, Meuwissen Theo H E
Institute for Animal Science and Health (ID-Lelystad), P.O. Box 65, 8200 AB Lelystad, The Netherlands.
Genet Sel Evol. 2002 Jan-Feb;34(1):23-39. doi: 10.1186/1297-9686-34-1-23.
Minimum coancestry mating with a maximum of one offspring per mating pair (MC1) is compared with random mating schemes for populations with overlapping generations. Optimum contribution selection is used, whereby DeltaF is restricted. For schemes with DeltaF restricted to 0.25% per year, 256 animals born per year and heritability of 0.25, genetic gain increased with 18% compared with random mating. The effect of MC1 on genetic gain decreased for larger schemes and schemes with a less stringent restriction on inbreeding. Breeding schemes hardly changed when omitting the iteration on the generation interval to find an optimum distribution of parents over age-classes, which saves computer time, but inbreeding and genetic merit fluctuated more before the schemes had reached a steady-state. When bulls were progeny tested, these progeny tested bulls were selected instead of the young bulls, which led to increased generation intervals, increased selection intensity of bulls and increased genetic gain (35% compared to a scheme without progeny testing for random mating). The effect of MC1 decreased for schemes with progeny testing. MC1 mating increased genetic gain from 11-18% for overlapping and 1-4% for discrete generations, when comparing schemes with similar genetic gain and size.
将每对交配最多产生一个后代的最小共同祖先交配(MC1)与具有重叠世代的群体的随机交配方案进行比较。采用最优贡献选择,从而限制ΔF。对于将ΔF限制为每年0.25%、每年出生256只动物且遗传力为0.25的方案,与随机交配相比,遗传进展提高了18%。对于更大规模的方案以及对近亲繁殖限制较宽松的方案,MC1对遗传进展的影响会降低。在寻找不同年龄组亲本的最优分布时,如果省略世代间隔的迭代,育种方案几乎不会改变,这节省了计算机时间,但在方案达到稳态之前,近亲繁殖和遗传价值的波动会更大。当公牛进行后裔测定时,选择这些经过后裔测定的公牛而非年轻公牛,这导致世代间隔增加、公牛选择强度增加以及遗传进展增加(与无后裔测定的随机交配方案相比增加了35%)。对于有后裔测定的方案,MC1的影响会降低。当比较具有相似遗传进展和规模的方案时,MC1交配使重叠世代的遗传进展提高了11 - 18%,离散世代提高了1 - 4%。