Kong Xiangqing, Cao Kejiang, Yang Rong, Xu Di, Sheng Yanhui, Huang Jun, Ma Wenzhu
Department of Cardiology, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
Chin Med J (Engl). 2002 Jan;115(1):126-8.
To evaluate the safety and efficacy of the Amplatzer septal occluder for transcatheter closure in patients with secundum atrial septal defect (ASD II).
Patients with clinically confirmed ASD II were recommended for transcatheter closure of ASD II.
30 ASD II patients (20 females) underwent transcatheter closure at a median age of 18.4 years (5-55 years). Both the stretched diameters of ASDs and the sizes of the devices were from 18 to 34 mm (25 +/- 7 mm). The successful placement rate was 100%. The rest shunt documented by color Doppler, was immediately after implantation in 40% of patients, in 9.9% after 24 hours, and in 3.3% trace at 3 months. No serious complications were observed. There was improvement in symptoms and in cardiac size. Septal motion abnormalities normalized in all patients after 3 months follow-up.
The Amplatzer septal occluder is a safe and effective device for transcatheter closure of ASD II. Long-term follow-up is still required before widespread clinical use can be recommended.
评估Amplatzer房间隔封堵器经导管封堵继发孔型房间隔缺损（ASD II）患者的安全性和有效性。
临床确诊为ASD II的患者被推荐行经导管封堵ASD II。
30例ASD II患者（20例女性）接受了经导管封堵，中位年龄为18.4岁（5 - 55岁）。ASD的伸展直径和封堵器尺寸均为18至34毫米（25±7毫米）。成功置入率为100%。彩色多普勒记录的残余分流情况为：植入后立即有残余分流的患者占40%，24小时后为9.9%，3个月时微量分流占3.3%。未观察到严重并发症。症状和心脏大小均有改善。随访3个月后，所有患者的房间隔运动异常均恢复正常。
Amplatzer房间隔封堵器是经导管封堵ASD II的一种安全有效的装置。在推荐广泛临床应用之前，仍需要进行长期随访。
