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[对于折返性结内交界性心动过速病例,慢径路射频消融能否预防心房颤动?]

[Does radiofrequency ablation of the slow pathway prevent atrial fibrillation in cases of re-entrant intranodal junctional tachycardia?].

作者信息

Brembilla-Perrot B, Beurrier D, Houriez P

机构信息

CHU de Brabois, rue du Morvan, 54500 Vandoeuvre-les-Nancy, France.

出版信息

Arch Mal Coeur Vaiss. 2002 Feb;95(2):97-101.

Abstract

The aim of this study was to assess the effects of ablation of the slow pathway on the eventual occurrence of atrial fibrillation (AF) in cases of intranodal junctional tachycardia (INJT). Two hundred and fifty seven patients were admitted for recurrent paroxysmal junctional tachycardia. The ages ranged from 15 to 87 years (average 54 +/- 16 years). Tachycardia was induced in all patients and the mechanism shown to be INJT in 215 patients. Twelve of these (6%) also had spontaneous paroxysmal AF. It was possible to induce INJT and AF in 23 patients during electrophysiological study (11%): of these patients, 4 had a history of AF associated with INJT. Radiofrequency ablation of the slow pathway was successfully carried out. Patients were followed up for 1 to 6 years (average 3 +/- 2 years). None were prescribed antiarrhythmic drugs. The results showed that of the 12 patients with spontaneous AF before ablation, 8 had recurrence of paroxysmal AF which required reintroduction of an antiarrhythmic treatment and a ninth patient is currently in chronic atrial fibrillation. All but one of the patients were over 65 years of age. The AF recurred 1 month to 4 years after ablation. Of the 19 patients without previous AF but with inducible AF, 2 developed spontaneous paroxysmal AF. Of the patients without previous AF and without inducible AF, 4 aged over 65 went on to develop paroxysmal AF. The authors conclude that radiofrequency ablation of the slow pathway of patients with INJT does not seem to prevent future development of AF in elderly subjects.

摘要

本研究的目的是评估在结内折返性心动过速(INJT)病例中,慢径路消融对心房颤动(AF)最终发生的影响。257例患者因反复发作的阵发性交界性心动过速入院。年龄范围为15至87岁(平均54±16岁)。所有患者均诱发了心动过速,其中215例患者的机制显示为INJT。其中12例(6%)也有自发性阵发性AF。在电生理研究期间,23例患者(11%)可诱发INJT和AF:这些患者中,4例有与INJT相关的AF病史。成功进行了慢径路的射频消融。对患者进行了1至6年的随访(平均3±2年)。均未给予抗心律失常药物。结果显示,在消融前有自发性AF的12例患者中,8例阵发性AF复发,需要重新使用抗心律失常治疗,第9例患者目前处于慢性心房颤动状态。除1例患者外,所有患者均年龄超过65岁。AF在消融后1个月至4年复发。在19例既往无AF但可诱发AF的患者中,2例发生了自发性阵发性AF。在既往无AF且不可诱发AF的患者中,4例年龄超过65岁的患者发生了阵发性AF。作者得出结论,INJT患者的慢径路射频消融似乎不能预防老年患者未来AF的发生。

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