Baviera Giovanni, D'Anna Rosario, Corrado Francesco, Ruello Antonella, Buemi Michele, Jasonni Valerio Maria
Departments of Gynecology and Internal Medicine, University of Messina, Messina, Italy.
J Reprod Med. 2002 Mar;47(3):191-3.
To determine if plasma and amniotic fluid levels of intercellular adhesion molecule-1 (ICAM-1) at 16 weeks' gestation could be predictive of preeclampsia or intrauterine growth retardation (IUGR).
A retrospective analysis was undertaken in 44 serum samples stored for Down's syndrome screening at 16 weeks' gestation and 44 amniotic fluid samples obtained by midtrimester amniocentesis.
No significant difference was found between women who subsequently developed preeclampsia or IUGR and the control group.
This study failed to demonstrate that ICAM-1 may be an early serum marker of preeclampsia or an amniotic fluid marker of IUGR.
确定妊娠16周时血浆和羊水细胞间黏附分子-1（ICAM-1）水平是否可预测子痫前期或胎儿宫内生长受限（IUGR）。
对妊娠16周时为进行唐氏综合征筛查而储存的44份血清样本以及孕中期羊膜腔穿刺获取的44份羊水样本进行回顾性分析。
随后发生子痫前期或IUGR的女性与对照组之间未发现显著差异。
本研究未能证明ICAM-1可能是子痫前期的早期血清标志物或IUGR的羊水标志物。
