Michels Jean-Jacques, Delcambre Corinne, Marnay Jacques, Denoux Yves, Peny Anne-Marie, Chasle Jacques
Service d'Anatomie Pathologique, Centre Francois Baclesse, 14076 Caen Cedex, France.
Ann Pathol. 2002 Feb;22(1):10-7.
During a both retrospective and prospective study of thyroid cancers treated in the Basse Normandie between 1960 and 1999, we have identified 32 patients with thyroid lymphoma. The correct diagnosis was made initially in 69% of all cases. In the other cases, the diagnosis was secondarily corrected after review of the pathological material. According to the REAL classification, 7 (21%) corresponded to low grade MALT lymphomas, 2 to low grade lymphomas, 10 to high grade MALT Lymphomas and 10 (31%) to high grade lymphomas, one plasmocytoma and two unclassified lymphomas. According to the Ann Arbor classification, stage was IE for 56%, IIE for 19%, IIIE for 3% and 9% for IV. Median survival was 28 months with a mean at 61 months. 20 patients died (62%), 12 from the lymphoma and 8 from intercurrent causes. The overall survival at 5 years was 36% (9 5% CI 16 54%). A comparison of our results with those of the literature was performed.
在对1960年至1999年间下诺曼底地区治疗的甲状腺癌进行回顾性和前瞻性研究期间，我们确定了32例甲状腺淋巴瘤患者。所有病例中，最初有69%的病例做出了正确诊断。在其他病例中，经病理材料复查后，诊断得到了二次纠正。根据REAL分类，7例（21%）为低度MALT淋巴瘤，2例为低度淋巴瘤，10例为高度MALT淋巴瘤，10例（31%）为高度淋巴瘤，1例浆细胞瘤和2例未分类淋巴瘤。根据Ann Arbor分类，56%为IE期，19%为IIE期，3%为IIIE期，9%为IV期。中位生存期为28个月，平均生存期为61个月。20例患者死亡（62%），12例死于淋巴瘤，8例死于并发原因。5年总生存率为36%（95%CI 16-54%）。我们将结果与文献结果进行了比较。
