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胸腺瘤合并重症肌无力患者中的自身免疫性胰腺炎样病变

Autoimmune-like pancreatitis in thymoma with myasthenia gravis.

作者信息

Colaut Flavio, Toniolo Lamberto, Sperti Cosimo, Pozzobon Maurizia, Scapinello Antonio, Sartori Carlo Augusto

机构信息

Dept. of Thoracic Surgery, City Hospital of Castelfranco Veneto, 31033 Castefranco Veneto, Treviso.

出版信息

Chir Ital. 2002 Jan-Feb;54(1):91-4.

PMID:11942018
Abstract

A patient with thymoma and myasthenia gravis admitted for surgery presented increased serum levels of pancreatic amylase and lipase. Suspecting a thymoma-related autoimmune disorder, autoantibody serum titers were determined: increased autoantibody titers to acetylcholine receptors, thyroglobulin, thyroperoxidase and pancreatic insulin were detected. After thymectomy the serum levels of pancreatic enzymes decreased rapidly. Myasthenia gravis symptoms also improved. To the best of our knowledge no similar cases have been reported in the literature.

摘要

一名因胸腺oma和重症肌无力入院接受手术的患者,其血清中胰淀粉酶和脂肪酶水平升高。怀疑是与胸腺oma相关的自身免疫性疾病,于是测定了自身抗体血清滴度:检测到抗乙酰胆碱受体、甲状腺球蛋白、甲状腺过氧化物酶和胰腺胰岛素的自身抗体滴度升高。胸腺切除术后,胰腺酶的血清水平迅速下降。重症肌无力症状也有所改善。据我们所知,文献中尚未报道过类似病例。 (注:这里thymoma未查到准确中文对应,暂保留英文)

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