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自我评定的分裂型认知、精神病症状与精神分裂症高危年轻人中精神分裂症的发病

Self-rated schizotypal cognitions, psychotic symptoms and the onset of schizophrenia in young people at high risk of schizophrenia.

作者信息

Miller P McC, Lawrie S M, Byrne M, Cosway R, Johnstone E C

机构信息

Department of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Morningside Park, Edinburgh EH10 5HF, UK.

出版信息

Acta Psychiatr Scand. 2002 May;105(5):341-5. doi: 10.1034/j.1600-0447.2002.1o175.x.

DOI:10.1034/j.1600-0447.2002.1o175.x
PMID:11942940
Abstract

OBJECTIVE

To examine the associations between the Rust Inventory of Schizotypal Cognitions (RISC) and psychotic symptoms measured by the Present State Examination (PSE) and to assess the predictive validity of the RISC for later onset of schizophrenia.

METHOD

A total of 154 subjects at high risk for schizophrenia but who were currently well, 35 well controls and 28 first episode schizophrenic patients were assessed on specified PSE symptoms and completed the RISC. A subsample of the high risk group was subsequently monitored for onset of schizophrenia over 39 months.

RESULTS

RISC scores at entry were significantly higher in subjects with psychotic symptoms on PSE. There were indications that high scorers on the RISC were likely to develop schizophrenia. However, less than half of those falling ill exhibited high RISC scores on entry.

CONCLUSION

The RISC scale is highly associated with presence of psychotic symptoms on PSE and high scorers may be at increased risk of schizophrenia onset.

摘要

目的

研究分裂型认知的拉斯特量表(RISC)与通过现况检查(PSE)所测量的精神病性症状之间的关联,并评估RISC对精神分裂症后期发病的预测效度。

方法

对总共154名精神分裂症高危但目前状况良好的受试者、35名健康对照者和28名首次发作的精神分裂症患者进行了特定PSE症状的评估,并完成了RISC测试。随后对高危组的一个子样本进行了39个月的监测,以观察精神分裂症的发病情况。

结果

PSE上有精神病性症状的受试者在入组时的RISC分数显著更高。有迹象表明,RISC得分高的人可能会患上精神分裂症。然而,患病者中不到一半在入组时表现出高RISC分数。

结论

RISC量表与PSE上的精神病性症状高度相关,得分高者患精神分裂症的风险可能增加。

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