Mattos Carla
Dept Molecular and Structural Biochemistry, North Carolina State University, 128 Polk Hall, Raleigh, NC 27695-7622, USA.
Trends Biochem Sci. 2002 Apr;27(4):203-8. doi: 10.1016/s0968-0004(02)02067-4.
Protein-water interactions are key to biological function. They have an underlying dynamic component that pervades the functional roles associated both with particular systems and with the properties of proteins in general. This article focuses on the specific ways in which the dynamics of water are important to protein structure, motion and adaptability to changes in the protein environment.
蛋白质与水的相互作用是生物功能的关键。它们具有潜在的动态成分,这种成分贯穿于与特定系统以及一般蛋白质特性相关的功能角色之中。本文重点关注水的动态特性对蛋白质结构、运动以及适应蛋白质环境变化的重要性的具体方式。