Jarrard L E
J Comp Physiol Psychol. 1975 Jul;89(5):400-8. doi: 10.1037/h0077049.
Involvement of the hippocampus in memory was studied in the rat by employing a retention task with and without interpolated activity. Rats with extensive damage to hippocampus were able to relearn a preoperatively acquired single-alternation task with savings and to perform the single alternation with relatively long delays at a level similar to that of control subjects. However, hippocampals were more affected than normals by an interpolated activity that interferes with retention. The finding of normal retention combined with increased susceptibility to interference supports the view that the memory impairment in subjects with damage to hippocampus may be due to an excess of interference among stored information.
通过采用有或没有插入活动的记忆保持任务，在大鼠身上研究了海马体在记忆中的作用。海马体受到广泛损伤的大鼠能够重新学习术前习得的单交替任务并有所节省，并且能够在与对照组相似的水平上以相对较长的延迟执行单交替任务。然而，海马体比正常大鼠更容易受到干扰记忆保持的插入活动的影响。正常记忆保持与对干扰敏感性增加相结合的这一发现支持了这样一种观点，即海马体受损的受试者的记忆损害可能是由于存储信息之间的干扰过多所致。
