Winocur G, Gilbert M
Behav Neural Biol. 1984 Jan;40(1):27-43. doi: 10.1016/s0163-1047(84)90146-8.
Two experiments are described in which groups of rats with bilateral hippocampal lesions, cortical lesions, and operated controls are compared on tests of discrimination learning, retention, and reversal learning. Experiment 1 examined the effects of varying prior training and context on new learning. Experiment 2 used a transfer paradigm to compare extent of original learning by hippocampal and control groups in a discrimination task involving multiple discriminanada . The major findings were that rats with hippocampal damage were less efficient at processing information and were more constrained by contextual influences than control rats.
本文描述了两项实验,在实验中对双侧海马损伤组、皮质损伤组和手术对照组的大鼠进行辨别学习、记忆保持和逆向学习测试并进行比较。实验1研究了不同的先前训练和环境对新学习的影响。实验2采用迁移范式,比较海马组和对照组在涉及多个辨别刺激的辨别任务中的原始学习程度。主要研究结果是,与对照组大鼠相比,海马损伤的大鼠在处理信息方面效率较低,且更容易受到环境影响的限制。